While I'm a huge fan of Madonna, I'm not such a huge fan of some of her film work. But, while staying in Pasadena, I thought I would check out the location used for the front of Simon's mansion for Who's That Girl (1987).
Here are links to other Madonna video or movie locations and shows:
Evening With Madonna - Smirnoff Nightlife Exchange Project
La Isla Bonita
Like A Prayer (video)
Like A Prayer (album)
Next Best Thing
What It Feels Like For A Girl
UPDATE April 2012: While near Oxnard, I decided to check out some of the train intersection locations...